The best 7mm is subjective to the end purpose...best for what? Efficiency? Accuracy? On-game performance? Smaller big game, or larger big game? All around performance or specialized performance?
Most will answer as to their "favourite" 7mm cartridge. This will be based on their individual experience with the various 7mm cartridges...and how many have used them all extensively enough to be able to give an educated answer.
(I have experience with and own rifles in the 7mm-08, 280 Rem, 7mm Rem Mag, and 7MM STW, shooting, handloading and hunting. I have shot the 7 Wby and RUM, but haven't handloaded or hunted with either. I now own a 7mm PRC but haven't made it to the range to sight it in yet. I also have not had the chance to shoot a 7x57 or 7x64 yet, or 275H&H. Although these are ballistic twins to the 7mm-08 and 280 Rem. My favourite is the 280 Rem, although I have shot more game with the 7MM STW, which I really like.)
Some have answered as to which chambering they have used the most...and in the end was that because of the chambering, or the rifle itself?
In either case, it is the "best", or favourite for them.