Guess I better get in on this since I am already involved.
Sure, the 30-06 will work just fine, with today's bullet technology you can get amazing penetration from some co called "light for caliber" bullets.Bonded or monolithic bullets can do some great things.150 or 165 grain would be plenty and shoot damn flat.
You could go the 7mm route as two-dogs suggests and have some bullets that are a bit more slippery if you want to flatten your bullet trajectory and have excellent penetration to boot.If you are shooting at distance you are going to have drop either way and knowing your distance as well as your bullet path will be your key to success for longer range applications.
A great deal is a great deal though and chambering isn't a huge issue these days(within reason of course).
Is the rifle comfortable for you? To me that is most important , if you have to struggle to get a comfortable grip/weld on the rifle then move on to the next one, keep trying till you find the sweet one.
As for range, that is shooter dependent, the chambering we are discussing will down large animals at long distances(400 yards and then some) IF the shooter can confidently hit his intended target the projectile will do it's job.
Anything .260 and up is suitable for an all purpose hunting rifle with today's bullets.Personally I'd go .308 over 30-06 , they are so close ballistically the animals will never know, but I prefer the SA rifles.
Yes, you can do plenty with the 7 oh 8 if you know how to use it.
As for ammo, just buy/load lots when it is time, nobody forgets ammo, and if you are 3 hours away from any shop with common ammo, you are still 3 hours away.Put a box in the truck and box in the rifle case, a box in the gym bag a box in your shaving kit, problem solved.
