I'll do better. Here is my choice for
all big game hunting in Canada in the varying conditions you describe:
You can see that the Muley was not too fond of it!
Remington Model 700 Stainless Mountain Rifle in .30-06, topped with a Bausch & Lomb Elite 3000 2-7X, pushing a 168-grain Barnes TSX at a chronographed 3,000+ fps into 3-shot groups that hover around 1 inch at 200 metres. (The secret is in the powder: Vihtavuori N560.)
I love to play around with different rifles and loads as much as the next guy. But this is my serious rifle that I rely upon almost every time I venture out to do big game hunting. Many of you may disagree with my choice (and that's the beauty of a free country), but I doubt that anyone is going to suggest that I'm incorrect to claim that this rifle/load combo will do it all in any deer hunting situation, from close in, low-light timber, to long-range sniping (the Muley above was taken from 300 yards across a deep draw).
There are also about a million other equally excellent do-all deer rifles out there. At the end of the day, it's what works for you (within certain paramenters, of course).