When you say everything is out of the frame but the locking block - you mean "everything"... no trigger housing, slide stop lever, springs, pins, Slide lock assembly, etc?
If so, you should be able to lay the grip frame upside down on a flat surface, and see if there are any anomalies in the four rails... one higher than the other etc... I've seen where the rails on one G22 pistol were almost pulled out of the frame... user error...