Who the hell practices pistol shooting at 50 yards anyway? If you can hit the paper at that range with 9/40/45, you're already ahead of the curve.
Focus on 15/25 yards: anything less than 2/2.5 inch groups at those distances is fantastic.
Wimp!
Remember that he was asking about shooting a .22 not a 9/40/45. Some have higher standards than others.
Wile I don't often shoot 50 yards with a handgun I have shot in an ISU Free Pistol event with a S&W model 41 with acceptable results. I did better than some of the guys with free pistols.
I also had an unusual event with a P38 at 50 meters.
I was at the range one time and I was going to shoot some plates with it. One of the old bullseye shooters suggested I shoot the plates at 50 meters. One hand, bullseye stance. The plates are 8" in diameter. I had reloads. No idea where the gun shot. So what the hell I gave it a try. Eight rounds in the mag. Careful aim and the first went down. Then the second, and third. Missed the fourth. Out of the eight rounds I knocked over six plates.
Now that gun has a gritty trigger. I would pull until I got to a rough part. Held the trigger while I took a couple of breaths then pulled again getting rid of a little more while aimed on the target. Between shot attempts I had constant pressure on the trigger. I didn't let up on the pressure. When the shot did go off it was due to a small increment in the trigger pull. The front sight is narrow by today's standard. This helped with the targets at 50m.
All with a standard Bullseye stance (shooting one handed) with a War issued P38. I would think that a good target pistol should be able to do much better. If you put an optical sight on the gun I'm sure it would be easier yet.
The more I practice the luckier I get.