I use the 140gr Hornday SP, CCI 200 primer and RE22 also in a T3.
45-46gr of RE22 has been VERY accurate and is not a 'high pressure' load. With 46gr I average 2535fps and every group I have fired has been sub MOA.
I dont have a manual with me now but the highest published load I have seen with 140gr jacket bullet and RE22 is in the Lee 2nd Ed manual and that is 48.1gr and I doubt very much that Lee would be publishing loads that exceed the SAAMI MAP of 51 kpsi for that cartridge. Of course some bullets will generate a little more pressure than others.