I admit I have not Moose hunted with a 44 Mag, but I've seen the results of some tests posted over the years on the levergunners forum, and the slower moving bullets (i.e., less than 1,800 fps) consistently seem to out-penetrate the modern high velocity bullets in actual meat, though they do not have the shock value that a high energy bullet does. I have the results of a very interesting Moose hunt this past fall involving a 44-40, a 375 H&H and a 458 Win Mag. I'm saving the details and photos for an article I hope to publish on the 44-40, but let's just say that the 44-40 performed beyond anyone's expectations. Of course, the hunter who used the 44-40, usually bags his Moose with a handgun, although in this case, that did not seem to be a factor. My point is that the slower heavy bullets can compete much better than people expect. I got 26" of penetration this past fall, including shattering the spine halfway through the bullet channel, with my 44-40 on a frontal shot Whitetail. The 44 Mag with a 265 bullet at 1,600 fps has 60 foot-pounds of momentum (which I have found to be a better indicator of penetration ability than muzzle energy). The 30-06 with a 180 grain bullet loaded to 2,600 fps has 66 foot pounds of momentum. That does predict it will give more penetration, but my point is that a 44 Mag firing a 265 grain bullet at 1,600 is still a very decent contender at ranges of 200 yards or less. My Moose hunting friend in Alaska indicates that there have been an awful lot of Moose taken by handgun hunters using the 44 Mag. A rifle will give a significant gain in power over a handgun. On the other hand, with the slow moving cartridges I use (1,300 fps to 1,400 fps), 200 yards is my upper limit. So, as you say, if it is a long shot out beyond 200 yards, the 44 Mag is a non-contender in my opinion. The kind of hunting I like to do however, (no scopes, old black powder cartridges) requires that I stalk to within 200 yards. That means I tend to take fewer animals averaged over the years, although recent years that has not been true. When all is said and done, there are certainly a lot more powerful, flatter shooting cartridges out there than the 44 Mag. The only reason to hunt Moose or anything else with a 44 Mag is if that is the only rifle a fellow has, or they really like the 44 Mag, in which case they need to hunt within the limitations of the cartridge.