Largest caliber you've shot a coyote with?

30-06 180gr made a mess. Later that same day a friend drilled a 'yote with his 375 H&H...I thought my 06 made a mess!
 
I've shot them with 45 Colt 255gr hard cast, .50 BP with 240gr projectile, 7mm Rem Mag with 139gr BTSP but the worst damage, like Brian46, was with a .243 with 87gr V-Max. Just about blew him in half.
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My deer guns do less damage than some varmint bullets I've tried. 7mm mag and 150 gr sierra gk and 140 accubond has been extremely fur friendly. Haven't shot one under 150 yards with them.
 
While living on the western prairie four years in the early 90's...

...'yotes with a friend's .300 Weatherby Mag.

...but then we'd go prairie dog shooting with .45-70's and a guy's .458 Win. Mag. too
 
Shot a pair with a 7mm mag. Went out and let a buddy use the 223 and had to clean up for him.


.270 while deer hunting a few years ago. Haven’t shot any this year been too busy ice fishing.

Any luck this year fishing? Been out a few times to a couple different spots and haven’t been very successful.
 
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