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The only one I've ever seen was in the last "Resident Evil" and I think the prop guy screwed up and put the wrong ammo out. I't would be a neat idea though.
According to the Wholesale Sports website they sell an 1873 Uberti in .45ACP... see the following broken link
w w w.wholesalesports.com/storefront/hunting/firearms/lever-action-rifles/1873-lever-action/prod229499.html
There is no such animal produced by any manufacturer on a regular cataloged item, but maybe there is a talented gunsmith out there who has done a conversion of some type. Can't hurt to ask!! good luck Dale in T-Bay