So far I know that I will be using BR2 primers, As a starting point I have decided I will first try 168gr Sierra MatchKings for paper or 168gr Hornady AMAX for hunting. I still have to decide on a powder; the top choices seem to be:
IMR 4895
H4895
IMR4064
BLC-2
I am leaning away from BLC-2 because it seems to be more popular with slightly lighter bullets, and I am (admittedly not for great reason) partial to Hodgdon and IMR powders. I am not at all concerned with metering because I don't use one, I very carefully spoon my powder onto the scale, and weigh it to 1/100 a grain.
Kombayotch: Why am I trying to match a powder to a primer? It is my belief, granted I am newer to reloading so I am still resting somewhat on others experience because I have yet to try enough combinations for myself, that each powder burns more consistently when paired with certain primers, and less consistently when paired with other primers. For this load I picked my primer first because it was the only match grade available to me, and was then trying to match the powder to it. I am glad to hear that you don't think I will have any bad powder/primer combinations. I am also glad that you mentioned the difference in average velocity between H4895 and the different primers was only 10fps, good to know. Maybe I am makinging to big of a deal over the primer/powder combination?
Sunray: I know the .308 win is a modest caliber of gopher gun, but I will set matters straight as soon as I wear out the barrell on my 7mm rem mag Remington 700 police gopher gun and have the rifle revamped into .338 lapua AI

For the record, I shoot gophers with every firearm I own; also for the record, I do not own any rimfire rifles or have any desire to. I do not mind spending a little more on rifle ammo. You know what Tim Taylor would say!