Yes. The 152mm HE were said to be able to brute force German tanks out of action even though they were not anti tank rounds. Definitely looked like the fuze set it off really fast rather than penetrating then going off.
An authority once told me a 155mm artillery shell is or was unable to knock out an average Western tank if it hit the tank. Such info is hard to come by and an authorized person probably would have access to such intel rather than a squaddie.
But, we know 152 mm rounds had catastrophic effects on WWII Axis tanks so some other factor is at play, whatever that is in this person's opinion.
The caption claimed this was a Panther tank turret hit with a 152mm shell. Don't know if it was in combat or a test, HE or AP. The ISU 152 was only a tank destroyer by accident. It was an assault gun mainly. I had heard the ISU was most successful when about three of them set up an ambush for the Axis tanks, or maybe firing from a place where they could appear, shoot, & quickly retire behind cover. They would have been formidable in an urban area where there were no range advantages.