The .300 Winchester Magnum likes a number of different powders, in my experience. The standouts are the usual favourites: Reloder 22, IMR 4350 and 4831, H4831 and H1000, etc.
Each has its own virtues and niche.
The classic load I've found that works in a number of rifles is any decent 180-grain bullet and 73 grains of IMR 4831. This combo always gives excellent velocity and accuracy, and it tends to be the first load I try when playing with a new .300.
For my hunting rifle these days, I've settled upon a slightly more exotic load: 77.5 grains of Vihtavuori N560, out of a Winchester case, ignited by a CCI 250, and pushing a Nosler 180-grain Accubond. My Sako has a short barrel (something like 22.5 inches). In spite of this, I'm getting a solid 3,050 fps over the chronograph and the first three shots land into about an inch at 200 metres. Last November, I absolutely flattened a Muley doe at a lasered 250 yards, with one shot through the spine (shooting down a steep canyon in central BC).
I agree with those who say that a .300 Winchester is a bit much for deer... but it sure works, though!
