As per some coaching that I am doing here - get really fussy "bang on" with some, get 0.1 grain variation - too much and too little - with some more. Shoot two groups at range - probably 5 shots each - more per group is likely more certain - can even shoot "round robin" one shot from one batch at one target, then next shot from next batch at other target, then repeat - will likely equalize out barrel fouling, barrel heat, lighting, wind and other esoteric issues. If you can see a difference, then you answered your own question for your shooting and your rifle. If you can not see a difference, then you also answered your question.
I am trying to encourage a learner to do reloading stuff that he can see makes difference on targets with his shooting skill and his stuff - might make a difference for someone else, with their ability and their stuff, but is not worth his time, unless he can show - to himself - how it makes a difference for him. For example - load up 10 identical rounds - shoot 5. Then "glass bed" that rifle - a week later come back and fire off the other 5 rounds - did the group get smaller? If yes, then was worth it - if no, then was not worth doing - if group got worse, maybe suggests that the process that was used needs work?
Load some rounds with .030" jump, and then some more with .020" jump - did that make a difference for groups on target, for shooter and his rifle? If not, is not worth fussing about - although might want to try that again in a year and see if it does, then.
Also need to appreciate there is "difference" and "statistically significant difference" - so fire a 2" 10 shot group at 100 yards - almost inevitably, in that group, will find two or three holes that are .250" apart. If you only shot those two or three - was "chance" that led you to claim 1/4 MOA - but you and that rifle are really 2 MOA - you more or less demonstrated that with your 10 shot 2 MOA group.