Where you put it matters more than which you use. Given the circumstances of a defense shooting, I doubt that the bear could tell the difference between a .338 and a .375 if both are loaded with good bullets. Twice I've carried a .338 M-70 while doing bear work, and in neither instance did I feel under gunned. If you're confident and competent with the .338 you know, that trumps the .375 you don't. But as far as ubiquitous cartridges go, as soon as you have a few hundred pieces of brass, its ubiquitous. I have about 400 pieces of brass for the .375 Ultra, 200 for the .375 Ruger, 500 for the .458, and 300 (thus far) for the 9.3X62. In my house, their ubiquitous.
If you do decide to go with the Savage, before you take the rifle into the field, strip the bolt, and you'll see a cross-pin just behind the bolt head that the firing pin passes through. Find some high quality cold temperature grease and smear that pin in it. It floats freely in its position in the bolt body, and if it begins to corrode and sticks slightly to one side or the other, it could put enough drag on the firing pin to cause a misfire. I saw that happen this summer to a Savage target gun . . . the Bush Rifle uses the same bolt design, and you don't want those sort of problems to occur in a dangerous bear scenario. If the rifle is going to be used for recreation and hunting the Savage is great, but if you are involved with bear work in a commercial capacity where you are protecting other people as well as yourself, you can't afford not to have better. If you don't like the Ruger, the CZ 550 is a good rifle, as its predecessor the Brno 602, and the new FN manufactured M-70 is a good rifle if mine is typical.