The G20 slide's about 40g heavier than the G21 slide, which is big enough to make a difference, but not nearly enough I'd be concerned. Just think the G29's slide has to be lighter still than the G21's, so not too much to get excited about. Mind you the G29's only 45g lighter than the G21, with a smaller mag and frame, so I suppose the slide's pretty beefy on that little bugger. Mechanically, the guns are the same, no reason why this is a bad idea as far as I'm concerned. I'd would stick to only running really hot loads through a G20 though to be safe.