Since this thread was revived, even if by a spammer troll:
Due to a computer failure I was without QuickLoad at an awkward time, choosing bullet/powder combinations for three rifles - 6mm GT, .223 Win, and .308 Win - so I tried GRT and QuickLoad Pro (the web-based QL).
GRT looks modern and is easy to use, but produced some outright dangerous numbers and pointed me at powders that no-one uses and away from those that are common.
QuickLoad Pro was unusable in the sense that I had to manually try each powder. I complained and did not receive a refund.
QuickLoad, now that I have it back, has produced guidance aligned with community experience in terms of common powders.
So it's QuickLoad for the win.