Longest uninterrupted taken out hunting is a 375H&H. Probably about a 14 year stretch with the exception of a hunt where the old weaver scope fogged and I had to take the 308, and for coyotes after November. Although the 375 has taken a good number of coyotes with minimal fur damage. Didn't plan on using it that much, but it worked so good and the balance of the rifle allows me to shoot it very well. Second is probably a tie between 308, 25-06, 7 rem mag, and 270wsm, at about 3 or 4 years each.