Dogleg, N160 has the advantage of being extremely consistent burning, leading to low ES velocities and harmonics repeatability from shot to shot and isn't bothered much by temperatures, other than extreme heat and cold.
My 338-06 loves it with 225 grain bullets, where it gives the best velocities and accuracy.
Same goes for the 280 Remington with monolithic bullets and cup/core bullets over 140 grains.
It prefers magnum primers, if you have them.
I used it for the 30-06 under 200 grain bullets and it gave the best velocity/accuracy combination there as well.
It's also one of the best powders to use in the 270Win with bullets 140 grains to 160 grains.
My 6.5x55 liked it as well with heavy bullets. In the Tikka T3, powder charges can be increased significantly for much better velocities than the books show, but even the book velocities, which are biased to the m96 type actions are very good with this powder.
VV powders tend to cover a wide range between their types, so it's not unusual to find that it may not be the best for velocities but accuracy is almost always better than expected, because of its incredibly consistent burn from shot to shot.
I know some shooters that won't shoot any other powders than VV and go to great lengths to get it.
It seems to be more available lately, especially online.