I have owned each of the calibers you mentioned except the WSM. I used to own a 300 win mag. They are all good choices. I have hunted deer and moose with them and more. With the quality of the ammunition available today I second the thread that said accuracy is more important. Ther used to be a saying "beware the man with one gun" I suggest you go to your local gunstore and try rifles that you like. Gohang out at a range and try and shoot one of each. FWIW I now use a 7-08 for deer, black bear, moose ,elk, and hopefully next year mountain goat. Excellent results so far and never felt undergunned.