Check the first post again,"I think the original question referred to what calibre/bullet would best go through brush to kill an animal seen screened through the brush"
Not sure I see this "between the lines".
For a "close range fast handling rifle/cartridge combo" (brush gun) to handle deer and moose, I like my Sav. 99 in .300 savage with a 2 to 7 power scope.
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I have a Rem. 7600 in .35 whelen with a low power variable as well.
Robin in Rocky
let's say deer and moose hunting at ranges from 20-60 yards?
I have read where more than one gun writer has set up targets behind brush and blazed away. The results I have seen were that calibre/bullet didn't make a great deal of difference. It appeared a 45-70, or similar, didn't do any better than a 308/30-06.
I have never taken game with any bush rifle that I have owned, but I always liked my Ruger Semi auto carbine in 44 mag. I'll have to buy another when I see the right deal.