My comparison was never meant to say what was absolutely possible. Just take any bullet, run the software at these velocities and see what happens. The chamberings were merely a point of reference so shooters could ball park. Any shooter can hot rod up or down to their own satisfaction. But the point still holds, alot more velocity per given bullet really doesn't change outcomes downrange (drop YES, drift - not so much). And yes, the FTR velocity is done all the time... and I am on the conservative side (don't recommend it but it is done every weekend all around the world)
If you go heavier, with possible higher BC, you up recoil... does that matter?
if you go bigger case volume, you most certainly increase bore wear... does that matter?
are the targets 3 moa or under moa?
does the shooter want a no brainer 'left edge' experience or want to drive the setup to the center of whatever target down range?
Just putting a counter viewpoint to the if you go far, go big. 1600yds isn't all that far with todays bullets... and a number of mid sized cases work just fine (assuming this is about S&Gs and not competing)
Jerry
PS, wrt to the small hard to hit vs big when it gets windy... shooting down at Rattlesnake range in Benton WA, you are going to get Hellalotta wind. And shooters using the anemic 155gr 30cal are eating out the center of a MOA sized target at 1000yds using a sling, elbows and open sights. In F class, X rings are hit all the time deliberately in winds that can approach 35mph... and that would be 1/2 MOA.
If you are going to shoot far, you better learn to read the wind... and if you have some indication of what the wind is doing and understand what it is telling you, wind is just a number on a dial.
And as for switching winds...
We had a bunch of PRS shooters compete with us to get some real world 1000yds practise. The person I was squadded with had a 300magnum launching ubber big (I think he was testing for the NF ELR challenge). At 1000yds, he had a really hard time keeping them inside the 9 ring (which is a 2 moa circle) with a number of shots reaching out to the 7ring which is a long ways from the center. Shots were up down, left right even when the winds were high but steady. Unsure what he was holding off but I doubt that combo was shooting anywhere near 1.5 MOA at distance.
He was stunned that I was stitching the X/10 ring (1/2 and 1 moa) with my itty bitty 308....