It seems to me that revolvers with leaf-springs are easier to get good trigger pulls on, especially double action triggers. The S&Ws, earlier Colts and the Pythons usually come with very good, or better, triggers right out of the box.
Personally I'm a Ruger fan; but you need to have work done to get good triggers on them.
In calibers, .22 rf would probably be best to start with; but if you are going centerfire, .357 mag, because you can still shoot cheap .38 spec. And once you start to reload it's very versatile.