No offense, but it doesn't sound like you know what you're talking about. If the "size of the hole" was the only thing that mattered, rifles would be pretty much useless.being light weight is almost of the most importance after reliability which is number one. If I survive my situation of a downed aircraft I will gladly by a new one.
I could try to argue for a 10 mm but a 45 acp will leave a bigger hole every single time.
In the real world, .45ACP is a poor choice for wilderness carry due to its low velocity. It doesn't matter how big of a hole it can theoretically make if it can't penetrate deep enough to strike vital organs. 10 mm would be a much better choice, though still not as good as the more powerful revolver calibers.