Fair enough...why stop at 458 Lott? Why not a 460 WBY or wildcat round like 475 A&M Magnum or a 577 Tyrannosaur?....not trying to be a smart a@@ just trying to understand
The answer comes down to bullet construction and velocity. Expanding bullets intended for use on heavy, thick skinned game, have thick jackets, even though they are intended to upset. A reality of terminal ballistics is that the higher the impact velocity and the greater the density of the target is, the faster the bullet upsets. So thick jackets are used in the bullets intended for heavy game that are typically loaded for the rounds you mention; the thick jackets slow the bullet's expansion even at high velocity, close range impacts on dense targets. This ensures deep penetration, even if its at the expense of wound diameter, which is less important on big and often dangerous African and Asiatic game.
Lets consider two extremes, a 55 gr .22-250 load and the traditional 405 gr .45/70 load. Both loads produce about 1700 ft-lbs of kinetic energy, and we'll assume that, for the purposes of discussion, the bullet impact of each generates the that amount of energy on the target. Kinetic energy is a measure of work, and provides a useful comparison in this example. The .22-250 bullet impacts at very high velocity expands rapidly, and sheds weight, both act to limit penetration, and create a very wide, though shallow, wound channel. The .45-70 bullet's impact velocity is only about a third of the .22-250's, and the bullet weighs seven times more, but it barely changes shape as it penetrates, so it sheds velocity at a much slower rate. If the target was large enough, you would see the .45/70's wound channel would be similar in volume to the .22-250's, but instead of being wide and shallow, its narrow and deep.
So to answer your question, a bullet fired from a .300 Winchester creates a wider, shallower wound than the big bores you mention. Despite the fact that the big bore's respective velocities are high for caliber, their bullet's typically have thick jackets intended to impede expansion, so expansion occurs slower, since penetration is more desirable on the heavy game they are intended for. If we consider the .375 H&H, its an ideal general purpose rifle for big game hunting anywhere in the world, having the penetration to kill the largest game, high velocity that produces a flat trajectory, but the thick jacketed bullets led to the often repeated quote, "You can eat right up to the bullet hole!" On the other hand, a .300 Winchester, with its high velocity and thin jacketed bullets, with a near range bullet impact, can turn 20 pounds of meat into inedible blood shot, jellied mush with a shoulder shot.