I can see a legitimate use for the smaller guns, 410 and 28g in sub gauge competitions but for hunting purposes I personally am not a fan. I own both 410 and 28g guns as well as 20, 12 and 10 gauge. IMO for hunting you are handicapping yourself with a 410 or a 28g. Just my experience and opinion, I know they have a loyal following but I am not impressed. Yes they kill at very short ranges but so will a slingshot. My nickname for a 410 is a “cripple stick” and find the 28g to be a glorified 410. I am referring to upland game hunting not waterfowl. They do not pattern as well or kill as well as a 20g in my experience and if the only reason to buy one is to save weight for carrying purposes there are light weight 20g guns that are available. When I was young my first shotgun was a borrowed Cooey single shot 12g. Kicked like a mule but killed like a bazooka

For me the 20g is the sweet spot for upland hunting but again just my opinion and experience, use whatever you like that works for you.