I love my Sig P226R, in .40S&W. This would be my first choice. I especially like the de-cocking lever for those times when a round must be in the chamber. I also like the external hammer for accurate shots. I've shot hundreds of rounds with my P226R, and I have never expienced a FTF, FTL, FTE or any other kind of failure. I would depend my life on it.