It depends on wether you reload your own ammo or not. If you don't then look for factory ammo using the nosler partition, barnes x, win. fail safe, swift a-frame, or bear claw. If you do reload, then get yourself some nosler partitions or fail safe bullets and load them hot. We are looking for muzzle velocity and down range energy here.Personally I would not veture out in grizzly country without anything less than a .338 win mag.