Depends on where I am hunting, have successfully used 308, 270 Win, 270 Wby, 22-250, 243 Win, 7x57, 7 Rem Mag, 32 Rem, 45-70, 348 Win, 30-30, 300 savage, all worked great. Thinking 25-35 for the bush work and 280 rem for open spaces this year but that could change. Probably my favourite is my Grad present of 81 a Winchester Fwt XTR 270 has taken a lot of game and still feels like "my" rifle, in my mind the 270 is perfectly suited to the big bodied mulies and whitetails in our area and varied hunting conditions.